A smart multiantenna gene theranostic system based on the programmed assembly of hypoxia-related siRNAs

The therapeutic application of small interfering RNA (siRNA) is challenging due to its non-specific targeting and delivery issues. Here, the authors report an endogenous micro-RNA guided and hybridisation chain reaction-promoted siRNA delivery system encapsulated in tumour-derived extracellular vesi...

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Autores principales: Xue Gong, Haizhou Wang, Ruomeng Li, Kaiyue Tan, Jie Wei, Jing Wang, Chen Hong, Jinhua Shang, Xiaoqing Liu, Jing Liu, Fuan Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/99f09402e8ee4a48bb32cbcf8f7b6811
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