Ileal Bile Acid Transporter Inhibitor Improves Hepatic Steatosis by Ameliorating Gut Microbiota Dysbiosis in NAFLD Model Mice

ABSTRACT Nonalcoholic fatty liver disease (NAFLD), characterized by excessive fat deposition in the liver unrelated to alcohol consumption, is highly prevalent worldwide. However, effective therapeutic agents approved for NAFLD treatment are lacking. An ileal bile acid transporter inhibitor (IBATi),...

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Bibliographic Details
Main Authors: Masahiro Matsui, Shinya Fukunishi, Takashi Nakano, Takaaki Ueno, Kazuhide Higuchi, Akira Asai
Format: article
Language:EN
Published: American Society for Microbiology 2021
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Online Access:https://doaj.org/article/9a0e2589159b4a369b5a6805e28b8614
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