Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver DiseaseSummary

Background & Aims: Alcohol-related liver disease (ALD) is characterized by accumulation of hepatic free fatty acids (FFAs) and triglyceride (TG)-enriched lipid droplets and cell death. The present study aimed to investigate how FFA or TG induces hepatocyte injury, thereby contributing to the...

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Autores principales: Wei Guo, Wei Zhong, Liuyi Hao, Haibo Dong, Xinguo Sun, Ruichao Yue, Tianjiao Li, Zhanxiang Zhou
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/9a339ec9927c4e4e9e9dcfcd791d6c62
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