Complete microtubule–kinetochore occupancy favours the segregation of merotelic attachments

Single microtubules (MTs) can move chromosomes, but it is unclear why kinetochores bind up to 20 MTs. Here, the authors decrease the number of kinetochore MTs with BAL27862 and see lagging chromosomes, suggesting that numerous kinetochore MTs provide force ensuring robust chromosomal segregation.

Guardado en:
Detalles Bibliográficos
Autores principales: Damian Dudka, Anna Noatynska, Chris A. Smith, Nicolas Liaudet, Andrew D. McAinsh, Patrick Meraldi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Q
Acceso en línea:https://doaj.org/article/9a3a7d104da04b9aaaf96e0d29c5129d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!