Transgenic mice overexpressing the LH receptor in the female reproductive system spontaneously develop endometrial tumour masses

Abstract The receptor for the luteinizing hormone (LH-R) is aberrantly over expressed in cancers of the reproductive system. To uncover whether LH-R over expression has a causative role in cancer, we generated a transgenic (TG) mouse which overexpresses the human LH-R (hLH-R) in the female reproduct...

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Autores principales: Tiziano Lottini, Jessica Iorio, Elena Lastraioli, Laura Carraresi, Claudia Duranti, Cesare Sala, Miriam Armenio, Ivo Noci, Serena Pillozzi, Annarosa Arcangeli
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9a6e45993e194c3c83cd4fdcbae104e0
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