Maternal but Not Infant Anti-HIV-1 Neutralizing Antibody Response Associates with Enhanced Transmission and Infant Morbidity

Maternal but Not Infant Anti-HIV-1 Neutralizing Antibody Response Associates with Enhanced Transmission and Infant Morbidity

ABSTRACT A significant number of infants acquire HIV-1 through their infected mother’s breast milk, primarily due to limited access to antiretrovirals. Passive immunization with neutralizing antibodies (nAbs) may prevent this transmission. Previous studies, however, have generated conflicting result...

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Bibliographic Details
Main Authors: Melissa Ghulam-Smith, Alex Olson, Laura F. White, Charles S. Chasela, Sascha R. Ellington, Athena P. Kourtis, Denise J. Jamieson, Gerald Tegha, Charles M. van der Horst, Manish Sagar
Format: article
Language:EN
Published: American Society for Microbiology 2017
Subjects:
HIV
MTCT
antibodies
breast milk
infant mortality
Microbiology
QR1-502
Online Access:https://doaj.org/article/9a80cb0441ee479eb38999a0594d3b71
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https://doaj.org/article/9a80cb0441ee479eb38999a0594d3b71

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