Identification of Piwil2-like (PL2L) proteins that promote tumorigenesis.

Identification of Piwil2-like (PL2L) proteins that promote tumorigenesis.

PIWIL2, a member of PIWI/AGO gene family, is expressed in the germline stem cells (GSCs) of testis for gametogenesis but not in adult somatic and stem cells. It has been implicated to play an important role in tumor development. We have previously reported that precancerous stem cells (pCSCs) consti...

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Main Authors: Yin Ye, De-Tao Yin, Li Chen, Quansheng Zhou, Rulong Shen, Gang He, Qingtao Yan, Zhenyu Tong, Andrew C Issekutz, Charles L Shapiro, Sanford H Barsky, Haifan Lin, Jian-Jian Li, Jian-Xin Gao
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2010
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/9a911db065244378b3e102cf91e5b5fd
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https://doaj.org/article/9a911db065244378b3e102cf91e5b5fd

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