Hypoxia promotes breast cancer cell invasion through HIF-1α-mediated up-regulation of the invadopodial actin bundling protein CSRP2
Abstract Hypoxia is a common feature of solid tumours that promotes invasion and metastatic dissemination. Invadopodia are actin-rich membrane protrusions that direct extracellular matrix proteolysis and facilitate tumour cell invasion. Here, we show that CSRP2, an invadopodial actin bundling protei...
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Autores principales: | , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/9aa369442f8843179906f34893c25651 |
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