Could Dampening Expression of the <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content> <italic toggle="yes">mtrCDE</italic>-Encoded Efflux Pump Be a Strategy To Preserve Currently or Resurrect Formerly Used Antibiotics To Treat Gonorrhea?

Could Dampening Expression of the <named-content content-type="genus-species">Neisseria gonorrhoeae</named-content> <italic toggle="yes">mtrCDE</italic>-Encoded Efflux Pump Be a Strategy To Preserve Currently or Resurrect Formerly Used Antibiotics To Treat Gonorrhea?

ABSTRACT Neisseria gonorrhoeae has developed resistance to every antibiotic introduced for treatment of gonorrhea since 1938, and concern now exists that gonorrheal infections may become refractory to all available antibiotics approved for therapy. The current recommended dual antibiotic treatment r...

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Autores principales: Shaochun Chen, Kristie L. Connolly, Corinne Rouquette-Loughlin, Alexander D’Andrea, Ann E. Jerse, William M. Shafer
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
Neisseria gonorrhoeae
efflux pumps
penicillin
transcriptional regulation
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/9ae04b887f90467b992a0deffeba228d
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