Intravenous delivery of targeted liposomes to amyloid-β pathology in APP/PSEN1 transgenic mice.
Extracellular amyloid-β (Aβ) plaques and intracellular neurofibrillary tangles constitute the major neuropathological hallmarks of Alzheimer's disease (AD). It is now apparent that parenchymal Aβ plaque deposition precedes behavioral signs of disease by several years. The development of agents...
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Autores principales: | , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/9ae082d361e647d9ae1ea922315f4efb |
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