Intravenous delivery of targeted liposomes to amyloid-β pathology in APP/PSEN1 transgenic mice.

Intravenous delivery of targeted liposomes to amyloid-β pathology in APP/PSEN1 transgenic mice.

Extracellular amyloid-β (Aβ) plaques and intracellular neurofibrillary tangles constitute the major neuropathological hallmarks of Alzheimer's disease (AD). It is now apparent that parenchymal Aβ plaque deposition precedes behavioral signs of disease by several years. The development of agents...

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Autores principales: Eric A Tanifum, Indrani Dasgupta, Mayank Srivastava, Rohan C Bhavane, Li Sun, John Berridge, Hoda Pourgarzham, Rashmi Kamath, Gabriela Espinosa, Stephen C Cook, Jason L Eriksen, Ananth Annapragada
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/9ae082d361e647d9ae1ea922315f4efb
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