Genetic and environmental influences interact with age and sex in shaping the human methylome
Differential impact of genetic and environmental influences on DNA methylation may result in sex- and age-related physiological variation and disease susceptibility. By analysing DNA methylome of 2,603 individuals from twin families, here, the authors establish a catalogue of between-individual vari...
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Nature Portfolio
2016
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oai:doaj.org-article:9ae2e648aa364593bf2830c06d53c07e2021-12-02T14:38:34ZGenetic and environmental influences interact with age and sex in shaping the human methylome10.1038/ncomms111152041-1723https://doaj.org/article/9ae2e648aa364593bf2830c06d53c07e2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11115https://doaj.org/toc/2041-1723Differential impact of genetic and environmental influences on DNA methylation may result in sex- and age-related physiological variation and disease susceptibility. By analysing DNA methylome of 2,603 individuals from twin families, here, the authors establish a catalogue of between-individual variation in DNA methylation.Jenny van DongenMichel G. NivardGonneke WillemsenJouke-Jan HottengaQuinta HelmerConor V. DolanErik A. EhliGareth E. DaviesMaarten van ItersonCharles E. BreezeStephan BeckBIOS ConsortiumH. Eka SuchimanRick JansenJoyce B. van MeursBastiaan T. HeijmansP. Eline SlagboomDorret I. BoomsmaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Jenny van Dongen Michel G. Nivard Gonneke Willemsen Jouke-Jan Hottenga Quinta Helmer Conor V. Dolan Erik A. Ehli Gareth E. Davies Maarten van Iterson Charles E. Breeze Stephan Beck BIOS Consortium H. Eka Suchiman Rick Jansen Joyce B. van Meurs Bastiaan T. Heijmans P. Eline Slagboom Dorret I. Boomsma Genetic and environmental influences interact with age and sex in shaping the human methylome |
| description |
Differential impact of genetic and environmental influences on DNA methylation may result in sex- and age-related physiological variation and disease susceptibility. By analysing DNA methylome of 2,603 individuals from twin families, here, the authors establish a catalogue of between-individual variation in DNA methylation. |
| format |
article |
| author |
Jenny van Dongen Michel G. Nivard Gonneke Willemsen Jouke-Jan Hottenga Quinta Helmer Conor V. Dolan Erik A. Ehli Gareth E. Davies Maarten van Iterson Charles E. Breeze Stephan Beck BIOS Consortium H. Eka Suchiman Rick Jansen Joyce B. van Meurs Bastiaan T. Heijmans P. Eline Slagboom Dorret I. Boomsma |
| author_facet |
Jenny van Dongen Michel G. Nivard Gonneke Willemsen Jouke-Jan Hottenga Quinta Helmer Conor V. Dolan Erik A. Ehli Gareth E. Davies Maarten van Iterson Charles E. Breeze Stephan Beck BIOS Consortium H. Eka Suchiman Rick Jansen Joyce B. van Meurs Bastiaan T. Heijmans P. Eline Slagboom Dorret I. Boomsma |
| author_sort |
Jenny van Dongen |
| title |
Genetic and environmental influences interact with age and sex in shaping the human methylome |
| title_short |
Genetic and environmental influences interact with age and sex in shaping the human methylome |
| title_full |
Genetic and environmental influences interact with age and sex in shaping the human methylome |
| title_fullStr |
Genetic and environmental influences interact with age and sex in shaping the human methylome |
| title_full_unstemmed |
Genetic and environmental influences interact with age and sex in shaping the human methylome |
| title_sort |
genetic and environmental influences interact with age and sex in shaping the human methylome |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/9ae2e648aa364593bf2830c06d53c07e |
| work_keys_str_mv |
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