Maltose-binding protein enhances secretion of recombinant human granzyme B accompanied by in vivo processing of a precursor MBP fusion protein.

<h4>Background</h4>The apoptosis-inducing serine protease granzyme B (GrB) is an important factor contributing to lysis of target cells by cytotoxic lymphocytes. Expression of enzymatically active GrB in recombinant form is a prerequisite for functional analysis and application of GrB fo...

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Autores principales: Benjamin Dälken, Robert A Jabulowsky, Pranav Oberoi, Itai Benhar, Winfried S Wels
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/9b058161300746e0baf7a7f5dc13a391
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