Kruppel like factor 10 up-regulates PDZ and LIM domain containing protein 2 via nuclear factor kappa-B pathway to inhibit proliferation and inflammatory of fibroblastoid synovial cell in rheumatoid arthritis

Kruppel like factor 10 up-regulates PDZ and LIM domain containing protein 2 via nuclear factor kappa-B pathway to inhibit proliferation and inflammatory of fibroblastoid synovial cell in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease caused by synovitis. Two genes, KLF10 (Kruppel like factor 10) and PDZ and LIM domain containing protein 2 (PDLIM2), play key roles in cell inflammation and proliferation. However, the specific roles of the two on inflammation and proliferation of R...

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Autores principales: Shan Wang, Xuwen Zha, Shengting Ruan, Shoulin Yao, Xiaoyu Zhang
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2021
Materias:
klf10
pdlim2
rheumatoid arthritis
fibroblastoid synovial cell
nf-κb pathway
proliferation
inflammatory
Biotechnology
TP248.13-248.65
Acceso en línea:https://doaj.org/article/9b11e8df1f664d549d2b6ff650b6f432
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https://doaj.org/article/9b11e8df1f664d549d2b6ff650b6f432

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