Unfolded protein response triggers differential apoptotic mechanisms in ovaries and early embryos exposed to maternal type 1 diabetes

Abstract Diabetes mellitus (DM) has profound effects on the female mammalian reproductive system, and early embryonic development, reducing female reproductive outcomes and inducing developmental programming in utero. However, the underlying cellular and molecular mechanisms remain poorly defined. A...

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Auteurs principaux: Aslı Okan, Necdet Demir, Berna Sozen
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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R
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Accès en ligne:https://doaj.org/article/9b2a5ea5188b4313862d827ba5e00982
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