Accurate detection of m6A RNA modifications in native RNA sequences

Accurate detection of m6A RNA modifications in native RNA sequences

We currently lack generic methods to map RNA modifications across the entire transcriptome. Here, the authors demonstrate that m6A RNA modifications can be detected with high accuracy using nanopore direct RNA sequencing.

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Detalles Bibliográficos
Autores principales: Huanle Liu, Oguzhan Begik, Morghan C. Lucas, Jose Miguel Ramirez, Christopher E. Mason, David Wiener, Schraga Schwartz, John S. Mattick, Martin A. Smith, Eva Maria Novoa
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/9b36004b41f44913a89a8cca26a8ff72
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https://doaj.org/article/9b36004b41f44913a89a8cca26a8ff72

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