Whole blood transcriptomic analysis reveals PLSCR4 as a potential marker for vaso-occlusive crises in sickle cell disease

Abstract Sickle cell disease, a common genetic blood disorder, results from a point mutation in the β-globin gene affecting the configuration of hemoglobin, predisposing to painful vaso-occlusive crisis (VOC) and multi-organ dysfunctions. There is a huge variation in the phenotypic expressions of SC...

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Autores principales: Hawra Abdulwahab, Muna Aljishi, Ameera Sultan, Ghada Al-Kafaji, Kannan Sridharan, Moiz Bakhiet, Safa Taha
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9b3673da8ad941a79b90412e2d704c82
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