Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age

Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age

Cognitive abilities tend to decline over time in advanced age, yet some individuals experience stable abilities or rapid decline. Here the authors present a proteome-wide association study of cognitive trajectory, and identify 38 proteins associated with cognitive resilience.

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Detalles Bibliográficos
Autores principales: Aliza P. Wingo, Eric B. Dammer, Michael S. Breen, Benjamin A. Logsdon, Duc M. Duong, Juan C. Troncosco, Madhav Thambisetty, Thomas G. Beach, Geidy E. Serrano, Eric M. Reiman, Richard J. Caselli, James J. Lah, Nicholas T. Seyfried, Allan I. Levey, Thomas S. Wingo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/9b58a9346e234b21a9e82096eeb3d508
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https://doaj.org/article/9b58a9346e234b21a9e82096eeb3d508

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