Dynamic interaction of TTDA with TFIIH is stabilized by nucleotide excision repair in living cells.

Transcription/repair factor IIH (TFIIH) is essential for RNA polymerase II transcription and nucleotide excision repair (NER). This multi-subunit complex consists of ten polypeptides, including the recently identified small 8-kDa trichothiodystrophy group A (TTDA)/ hTFB5 protein. Patients belonging...

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Auteurs principaux: Giuseppina Giglia-Mari, Catherine Miquel, Arjan F Theil, Pierre-Olivier Mari, Deborah Hoogstraten, Jessica M Y Ng, Christoffel Dinant, Jan H J Hoeijmakers, Wim Vermeulen
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2006
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Accès en ligne:https://doaj.org/article/9b5cec00a6f2471d8895e60b61883ddf
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