Route of administration of the TLR9 agonist CpG critically determines the efficacy of cancer immunotherapy in mice.
<h4>Background</h4>The TLR9 agonist CpG is increasingly applied in preclinical and clinical studies as a therapeutic modality to enhance tumor immunity. The clinical application of CpG appears, however, less successful than would be predicted from animal studies. One reason might be the...
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Main Authors: | , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2009
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Subjects: | |
Online Access: | https://doaj.org/article/9b71579ac2cc4de8ab648b64648303bf |
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