Identification of a genomic reservoir for new TRIM genes in primate genomes.

Tripartite Motif (TRIM) ubiquitin ligases act in the innate immune response against viruses. One of the best characterized members of this family, TRIM5α, serves as a potent retroviral restriction factor with activity against HIV. Here, we characterize what are likely to be the youngest TRIM genes i...

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Auteurs principaux: Kyudong Han, Dianne I Lou, Sara L Sawyer
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
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Accès en ligne:https://doaj.org/article/9b73b9ac21464bd89d278340b825e83d
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