Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle

The adult mammalian heart exhibits stubbornly low levels of cardiomyocyte proliferation, leading to high morbidity after injury or heart attack. Here the authors develop an approach for tracking cardiomyocyte cell cycling and show that the majority are located adjacent to the endocardium.

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Auteurs principaux: Xiuxiu Liu, Wenjuan Pu, Lingjuan He, Yan Li, Huan Zhao, Yi Li, Kuo Liu, Xiuzhen Huang, Wendong Weng, Qing-Dong Wang, Linghong Shen, Tao Zhong, Kun Sun, Reza Ardehali, Ben He, Bin Zhou
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/9b8cfcb5d01c4d9e967a80999d728db7
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