Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle

The adult mammalian heart exhibits stubbornly low levels of cardiomyocyte proliferation, leading to high morbidity after injury or heart attack. Here the authors develop an approach for tracking cardiomyocyte cell cycling and show that the majority are located adjacent to the endocardium.

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Autores principales:	Xiuxiu Liu, Wenjuan Pu, Lingjuan He, Yan Li, Huan Zhao, Yi Li, Kuo Liu, Xiuzhen Huang, Wendong Weng, Qing-Dong Wang, Linghong Shen, Tao Zhong, Kun Sun, Reza Ardehali, Ben He, Bin Zhou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/9b8cfcb5d01c4d9e967a80999d728db7
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spelling	oai:doaj.org-article:9b8cfcb5d01c4d9e967a80999d728db72021-12-02T17:37:13ZCell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle10.1038/s41467-021-25933-52041-1723https://doaj.org/article/9b8cfcb5d01c4d9e967a80999d728db72021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25933-5https://doaj.org/toc/2041-1723The adult mammalian heart exhibits stubbornly low levels of cardiomyocyte proliferation, leading to high morbidity after injury or heart attack. Here the authors develop an approach for tracking cardiomyocyte cell cycling and show that the majority are located adjacent to the endocardium.Xiuxiu LiuWenjuan PuLingjuan HeYan LiHuan ZhaoYi LiKuo LiuXiuzhen HuangWendong WengQing-Dong WangLinghong ShenTao ZhongKun SunReza ArdehaliBen HeBin ZhouNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiuxiu Liu Wenjuan Pu Lingjuan He Yan Li Huan Zhao Yi Li Kuo Liu Xiuzhen Huang Wendong Weng Qing-Dong Wang Linghong Shen Tao Zhong Kun Sun Reza Ardehali Ben He Bin Zhou Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle
description	The adult mammalian heart exhibits stubbornly low levels of cardiomyocyte proliferation, leading to high morbidity after injury or heart attack. Here the authors develop an approach for tracking cardiomyocyte cell cycling and show that the majority are located adjacent to the endocardium.
format	article
author	Xiuxiu Liu Wenjuan Pu Lingjuan He Yan Li Huan Zhao Yi Li Kuo Liu Xiuzhen Huang Wendong Weng Qing-Dong Wang Linghong Shen Tao Zhong Kun Sun Reza Ardehali Ben He Bin Zhou
author_facet	Xiuxiu Liu Wenjuan Pu Lingjuan He Yan Li Huan Zhao Yi Li Kuo Liu Xiuzhen Huang Wendong Weng Qing-Dong Wang Linghong Shen Tao Zhong Kun Sun Reza Ardehali Ben He Bin Zhou
author_sort	Xiuxiu Liu
title	Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle
title_short	Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle
title_full	Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle
title_fullStr	Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle
title_full_unstemmed	Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle
title_sort	cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/9b8cfcb5d01c4d9e967a80999d728db7
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Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle

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