Mechanistic action of weak acid drugs on biofilms

Abstract Selective permeability of a biofilm matrix to some drugs has resulted in the development of drug tolerant bacteria. Here we studied the efficacy of a weak organic acid drug, N-acetyl-L-cysteine (NAC), on the eradication of biofilms formed by the mucoid strain of Pseudomonas aeruginosa and i...

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Autores principales: Binu Kundukad, Megan Schussman, Kaiyuan Yang, Thomas Seviour, Liang Yang, Scott A. Rice, Staffan Kjelleberg, Patrick S. Doyle
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/9b8e138e560d4001bbb139f09e7bce07
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