Mechanistic action of weak acid drugs on biofilms
Abstract Selective permeability of a biofilm matrix to some drugs has resulted in the development of drug tolerant bacteria. Here we studied the efficacy of a weak organic acid drug, N-acetyl-L-cysteine (NAC), on the eradication of biofilms formed by the mucoid strain of Pseudomonas aeruginosa and i...
Guardado en:
Autores principales: | Binu Kundukad, Megan Schussman, Kaiyuan Yang, Thomas Seviour, Liang Yang, Scott A. Rice, Staffan Kjelleberg, Patrick S. Doyle |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/9b8e138e560d4001bbb139f09e7bce07 |
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