Molecular basis for the dual function of Eps8 on actin dynamics: bundling and capping.

Actin capping and cross-linking proteins regulate the dynamics and architectures of different cellular protrusions. Eps8 is the founding member of a unique family of capping proteins capable of side-binding and bundling actin filaments. However, the structural basis through which Eps8 exerts these f...

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Autores principales: Maud Hertzog, Francesca Milanesi, Larnele Hazelwood, Andrea Disanza, HongJun Liu, Emilie Perlade, Maria Grazia Malabarba, Sebastiano Pasqualato, Alessio Maiolica, Stefano Confalonieri, Christophe Le Clainche, Nina Offenhauser, Jennifer Block, Klemens Rottner, Pier Paolo Di Fiore, Marie-France Carlier, Niels Volkmann, Dorit Hanein, Giorgio Scita
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/9bb2acf482a74833be574542c89fb8d3
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