International Normalized Ratio (INR) Increases amongst Two Patients Living with HIV on Warfarin after Being Switched from a Nevirapine to a Dolutegravir-Based Antiretroviral Regimen
The increased use of dolutegravir-based regimens in the treatment of HIV is unmasking drug interactions, particularly in patients who were previously on nevirapine. Nevirapine is an enzyme inducer and increases the dosing requirements for cytochrome P450 enzyme substrates including warfarin. Upon di...
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| Main Authors: | , , |
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| Format: | article |
| Language: | EN |
| Published: |
Hindawi Limited
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/9bc0bab08f95454ba24963febdf7e261 |
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