Totipotency segregates between the sister blastomeres of two-cell stage mouse embryos

Abstract Following fertilization in mammals, it is generally accepted that totipotent cells are exclusive to the zygote and to each of the two blastomeres originating from the first mitotic division. This model of totipotency was inferred from a minority of cases in which blastomeres produced monozy...

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Bibliographic Details
Main Authors: E. Casser, S. Israel, A. Witten, K. Schulte, S. Schlatt, V. Nordhoff, M. Boiani
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/9bc89992ffab4344a934c2ab63e4089a
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