A mitochondria-dependent pathway mediates the apoptosis of GSE-induced yeast.

Grapefruit seed extract (GSE), which has powerful anti-fungal activity, can induce apoptosis in S. cerevisiae. The yeast cells underwent apoptosis as determined by testing for apoptotic markers of DNA cleavage and typical chromatin condensation by Terminal Deoxynucleotidyl Transferase-mediated dUTP...

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Auteurs principaux: Sishuo Cao, Wentao Xu, Nan Zhang, Yan Wang, YunBo Luo, Xiaoyun He, Kunlun Huang
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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Accès en ligne:https://doaj.org/article/9be106998b124be9a897447536ddd7b4
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