Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells

Spermatogonial stem cells (SSCs) spontaneously convert to multipotent adult spermatogonial-derived stem cells (MASCs). Here, the authors reveal the dynamics of bivalent histone H3-lysine4 and -lysine27 methylation signatures at somatic gene promoters in SSCs and ESC-like promoter chromatin states in...

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Autores principales: Ying Liu, Eugenia G. Giannopoulou, Duancheng Wen, Ilaria Falciatori, Olivier Elemento, C. David Allis, Shahin Rafii, Marco Seandel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/9be23f62cde04e9eb501aca199051c3d
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