Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells

Spermatogonial stem cells (SSCs) spontaneously convert to multipotent adult spermatogonial-derived stem cells (MASCs). Here, the authors reveal the dynamics of bivalent histone H3-lysine4 and -lysine27 methylation signatures at somatic gene promoters in SSCs and ESC-like promoter chromatin states in...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ying Liu, Eugenia G. Giannopoulou, Duancheng Wen, Ilaria Falciatori, Olivier Elemento, C. David Allis, Shahin Rafii, Marco Seandel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/9be23f62cde04e9eb501aca199051c3d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:9be23f62cde04e9eb501aca199051c3d
record_format dspace
spelling oai:doaj.org-article:9be23f62cde04e9eb501aca199051c3d2021-12-02T17:32:50ZEpigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells10.1038/ncomms112752041-1723https://doaj.org/article/9be23f62cde04e9eb501aca199051c3d2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11275https://doaj.org/toc/2041-1723Spermatogonial stem cells (SSCs) spontaneously convert to multipotent adult spermatogonial-derived stem cells (MASCs). Here, the authors reveal the dynamics of bivalent histone H3-lysine4 and -lysine27 methylation signatures at somatic gene promoters in SSCs and ESC-like promoter chromatin states in MASCs.Ying LiuEugenia G. GiannopoulouDuancheng WenIlaria FalciatoriOlivier ElementoC. David AllisShahin RafiiMarco SeandelNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ying Liu
Eugenia G. Giannopoulou
Duancheng Wen
Ilaria Falciatori
Olivier Elemento
C. David Allis
Shahin Rafii
Marco Seandel
Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells
description Spermatogonial stem cells (SSCs) spontaneously convert to multipotent adult spermatogonial-derived stem cells (MASCs). Here, the authors reveal the dynamics of bivalent histone H3-lysine4 and -lysine27 methylation signatures at somatic gene promoters in SSCs and ESC-like promoter chromatin states in MASCs.
format article
author Ying Liu
Eugenia G. Giannopoulou
Duancheng Wen
Ilaria Falciatori
Olivier Elemento
C. David Allis
Shahin Rafii
Marco Seandel
author_facet Ying Liu
Eugenia G. Giannopoulou
Duancheng Wen
Ilaria Falciatori
Olivier Elemento
C. David Allis
Shahin Rafii
Marco Seandel
author_sort Ying Liu
title Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells
title_short Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells
title_full Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells
title_fullStr Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells
title_full_unstemmed Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells
title_sort epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/9be23f62cde04e9eb501aca199051c3d
work_keys_str_mv AT yingliu epigeneticprofilessignifycellfateplasticityinunipotentspermatogonialstemandprogenitorcells
AT eugeniaggiannopoulou epigeneticprofilessignifycellfateplasticityinunipotentspermatogonialstemandprogenitorcells
AT duanchengwen epigeneticprofilessignifycellfateplasticityinunipotentspermatogonialstemandprogenitorcells
AT ilariafalciatori epigeneticprofilessignifycellfateplasticityinunipotentspermatogonialstemandprogenitorcells
AT olivierelemento epigeneticprofilessignifycellfateplasticityinunipotentspermatogonialstemandprogenitorcells
AT cdavidallis epigeneticprofilessignifycellfateplasticityinunipotentspermatogonialstemandprogenitorcells
AT shahinrafii epigeneticprofilessignifycellfateplasticityinunipotentspermatogonialstemandprogenitorcells
AT marcoseandel epigeneticprofilessignifycellfateplasticityinunipotentspermatogonialstemandprogenitorcells
_version_ 1718380204826558464