Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells
Spermatogonial stem cells (SSCs) spontaneously convert to multipotent adult spermatogonial-derived stem cells (MASCs). Here, the authors reveal the dynamics of bivalent histone H3-lysine4 and -lysine27 methylation signatures at somatic gene promoters in SSCs and ESC-like promoter chromatin states in...
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Nature Portfolio
2016
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oai:doaj.org-article:9be23f62cde04e9eb501aca199051c3d2021-12-02T17:32:50ZEpigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells10.1038/ncomms112752041-1723https://doaj.org/article/9be23f62cde04e9eb501aca199051c3d2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11275https://doaj.org/toc/2041-1723Spermatogonial stem cells (SSCs) spontaneously convert to multipotent adult spermatogonial-derived stem cells (MASCs). Here, the authors reveal the dynamics of bivalent histone H3-lysine4 and -lysine27 methylation signatures at somatic gene promoters in SSCs and ESC-like promoter chromatin states in MASCs.Ying LiuEugenia G. GiannopoulouDuancheng WenIlaria FalciatoriOlivier ElementoC. David AllisShahin RafiiMarco SeandelNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
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Science Q Ying Liu Eugenia G. Giannopoulou Duancheng Wen Ilaria Falciatori Olivier Elemento C. David Allis Shahin Rafii Marco Seandel Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells |
description |
Spermatogonial stem cells (SSCs) spontaneously convert to multipotent adult spermatogonial-derived stem cells (MASCs). Here, the authors reveal the dynamics of bivalent histone H3-lysine4 and -lysine27 methylation signatures at somatic gene promoters in SSCs and ESC-like promoter chromatin states in MASCs. |
format |
article |
author |
Ying Liu Eugenia G. Giannopoulou Duancheng Wen Ilaria Falciatori Olivier Elemento C. David Allis Shahin Rafii Marco Seandel |
author_facet |
Ying Liu Eugenia G. Giannopoulou Duancheng Wen Ilaria Falciatori Olivier Elemento C. David Allis Shahin Rafii Marco Seandel |
author_sort |
Ying Liu |
title |
Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells |
title_short |
Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells |
title_full |
Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells |
title_fullStr |
Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells |
title_full_unstemmed |
Epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells |
title_sort |
epigenetic profiles signify cell fate plasticity in unipotent spermatogonial stem and progenitor cells |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/9be23f62cde04e9eb501aca199051c3d |
work_keys_str_mv |
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_version_ |
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