Integrated analysis of patients with KEAP1/NFE2L2/CUL3 mutations in lung adenocarcinomas

Integrated analysis of patients with KEAP1/NFE2L2/CUL3 mutations in lung adenocarcinomas

Abstract Objectives To explore the clinical features, molecular characteristics, and immune landscape of lung adenocarcinoma patients with KEAP1/NFE2L2/CUL3 mutations. Methods The multi‐omics data from the GDC‐TCGA LUAD project of The Cancer Genome Atlas (TCGA) database were downloaded from the Xena...

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Autores principales: Xing Jin, Yuansheng Zheng, Zhencong Chen, Fei Wang, Guoshu Bi, Ming Li, Jiaqi Liang, Qihai Sui, Yunyi Bian, Zhengyang Hu, Yulei Qiao, Songtao Xu
Formato: article
Lenguaje:EN
Publicado: Wiley 2021
Materias:
cullin 3 (CUL3)
kelch‐like ECH‐associated protein 1 (KEAP1)
lung adenocarcinoma (LUAD)
mutation
nuclear factor erythroid 2‐like 2 (NFE2L2)
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/9bf3bd92b7a34467a1b86e2ceee31faf
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https://doaj.org/article/9bf3bd92b7a34467a1b86e2ceee31faf

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