Is Ferroptosis a Key Component of the Process Leading to Multiorgan Damage in COVID-19?

Is Ferroptosis a Key Component of the Process Leading to Multiorgan Damage in COVID-19?

Even though COVID-19 is mostly well-known for affecting respiratory pathology, it can also result in several extrapulmonary manifestations, leading to multiorgan damage. A recent reported case of SARS-CoV-2 myocarditis with cardiogenic shock showed a signature of myocardial and kidney ferroptosis, a...

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Autores principales: Anna Maria Fratta Pasini, Chiara Stranieri, Domenico Girelli, Fabiana Busti, Luciano Cominacini
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
ferroptosis
COVID-19
multiorgan damage
iron
GSH-GPX4 axis
oxidative stress
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/9c055f6238c048f28066693d2e186dc6
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https://doaj.org/article/9c055f6238c048f28066693d2e186dc6

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