NFκB activation in differentiating glioblastoma stem-like cells is promoted by hyaluronic acid signaling through TLR4

Abstract We have previously described that the NFκB pathway is upregulated during differentiation of glioblastoma stem-like cells (GSCs) which keeps differentiating GSCs in a proliferative astrocytic precursor state. However, extracellular signals and cellular mediators of this pathway are not clear...

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Autores principales: Eva Ferrandez, Olga Gutierrez, David San Segundo, Jose L. Fernandez-Luna
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/9c154a045e8d4b4dbe4f141ef5005fdb
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