Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2.

Wnt signalling is a key pathway controlling bone formation in mice and humans. One of the regulators of this pathway is Dkk1, which antagonizes Wnt signalling through the formation of a ternary complex with the transmembrane receptors Krm1/2 and Lrp5/6, thereby blocking the induction of Wnt signalli...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Jochen Schulze, Sebastian Seitz, Hiroaki Saito, Michael Schneebauer, Robert P Marshall, Anke Baranowsky, Bjoern Busse, Arndt F Schilling, Felix W Friedrich, Joachim Albers, Alexander S Spiro, Jozef Zustin, Thomas Streichert, Kristina Ellwanger, Christof Niehrs, Michael Amling, Roland Baron, Thorsten Schinke
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2010
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/9c6c239f6c7a4a1fab9fd5114bc3cb72
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Sea el primero en dejar un comentario!

Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2.

Ejemplares similares