Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk

Human antibodies cross-reactive for several viruses within the Ebolavirus genus have been identified. Here the authors present the crystal structure of such a neutralizing monoclonal antibody (mAb) targeting the stalk of Bundibugyo virus glycoprotein and show that mAb binding may interfere with trim...

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Autores principales: Liam B. King, Brandyn R. West, Crystal L. Moyer, Pavlo Gilchuk, Andrew Flyak, Philipp A. Ilinykh, Robin Bombardi, Sean Hui, Kai Huang, Alexander Bukreyev, James E. Crowe, Erica Ollmann Saphire
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/9c896c7320b3408db2980180804deb30
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