'Death and axes': unexpected Ca²⁺ entry phenologs predict new anti-schistosomal agents.

Schistosomiasis is a parasitic flatworm disease that infects 200 million people worldwide. The drug praziquantel (PZQ) is the mainstay therapy but the target of this drug remains ambiguous. While PZQ paralyses and kills parasitic schistosomes, in free-living planarians PZQ caused an unusual axis dup...

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Autores principales: John D Chan, Prince N Agbedanu, Mostafa Zamanian, Sarah M Gruba, Christy L Haynes, Timothy A Day, Jonathan S Marchant
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/9ccdf22336a74c7a84f85be21f6a44b8
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