'Death and axes': unexpected Ca²⁺ entry phenologs predict new anti-schistosomal agents.

Schistosomiasis is a parasitic flatworm disease that infects 200 million people worldwide. The drug praziquantel (PZQ) is the mainstay therapy but the target of this drug remains ambiguous. While PZQ paralyses and kills parasitic schistosomes, in free-living planarians PZQ caused an unusual axis dup...

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Auteurs principaux: John D Chan, Prince N Agbedanu, Mostafa Zamanian, Sarah M Gruba, Christy L Haynes, Timothy A Day, Jonathan S Marchant
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/9ccdf22336a74c7a84f85be21f6a44b8
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