PEI-PEG-Coated Mesoporous Silica Nanoparticles Enhance the Antitumor Activity of Tanshinone IIA and Serve as a Gene Transfer Vector

Tanshinone IIA (TanIIA) and gene therapy both hold promising potentials in hepatocellular carcinoma (HCC) treatment. However, low solubility and poor bioavailability of TanIIA limit its clinical application. Similarly, gene therapy with GPC3-shRNA, a type of short hairpin RNAs (shRNAs) capable of si...

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Bibliographic Details
Main Authors: Yinxing Zhu, Miao Yue, Ting Guo, Fang Li, Zhifeng Li, Dazhuang Yang, Mei Lin
Format: article
Language:EN
Published: Hindawi Limited 2021
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Online Access:https://doaj.org/article/9cd4334b648c491a96fa2088c1caf127
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