Myeloid Protease-Activated Receptor-2 Contributes to Influenza A Virus Pathology in Mice

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Myeloid Protease-Activated Receptor-2 Contributes to Influenza A Virus Pathology in Mice

BackgroundInnate immune responses to influenza A virus (IAV) infection are initiated in part by toll-like receptor 3 (TLR3). TLR3-dependent signaling induces an antiviral immune response and an NFκB-dependent inflammatory response. Protease-activated receptor 2 (PAR2) inhibits the antiviral response...

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Autores principales:	Randall C. Gunther, Vanthana Bharathi, Stephen D. Miles, Lauryn R. Tumey, Clare M. Schmedes, Kohei Tatsumi, Meagan D. Bridges, David Martinez, Stephanie A. Montgomery, Melinda A. Beck, Eric Camerer, Nigel Mackman, Silvio Antoniak
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	toll-like receptor 3 influenza A virus innate immune response macrophage lung epithelial cell protease-activated receptor 2 (PAR2) Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/9ce01fde26334c13975a5e0be80b3539
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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