The Nestin neural enhancer is essential for normal levels of endogenous Nestin in neuroprogenitors but is not required for embryo development.

Enhancers are vitally important during embryonic development to control the spatial and temporal expression of genes. Recently, large scale genome projects have identified a vast number of putative developmental regulatory elements. However, the proportion of these that have been functionally assess...

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Autores principales: Ella Thomson, Ruby Dawson, Chee Ho H'ng, Fatwa Adikusuma, Sandra Piltz, Paul Q Thomas
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/9cf4d4f009da49f8b62d4a8421930bbe
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