Evolving Antibiotics against Resistance: a Potential Platform for Natural Product Development?

ABSTRACT To avoid an antibiotic resistance crisis, we need to develop antibiotics at a pace that matches the rate of evolution of resistance. However, the complex functions performed by antibiotics—combining, e.g., penetration of membranes, counteraction of resistance mechanisms, and interaction wit...

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Bibliographic Details
Main Authors: Kristofer Wollein Waldetoft, James Gurney, Joseph Lachance, Paul A. Hoskisson, Sam P. Brown
Format: article
Language:EN
Published: American Society for Microbiology 2019
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Online Access:https://doaj.org/article/9d054285540b4a4da2cf1d3dbac81a9c
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