IRF7 and RNH1 are modifying factors of HIV-1 reservoirs: a genome-wide association analysis

IRF7 and RNH1 are modifying factors of HIV-1 reservoirs: a genome-wide association analysis

Abstract Background Combination antiretroviral treatment (cART) cannot eradicate HIV-1 from the body due to the establishment of persisting viral reservoirs which are not affected by therapy and reinitiate new rounds of HIV-1 replication after treatment interruption. These HIV-1 reservoirs mainly co...

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Détails bibliographiques
Auteurs principaux: Zhenhua Zhang, Wim Trypsteen, Marc Blaauw, Xiaojing Chu, Sofie Rutsaert, Linos Vandekerckhove, Wouter van der Heijden, Jéssica Cristina dos Santos, Cheng-Jian Xu, Morris A. Swertz, Andre van der Ven, Yang Li
Format: article
Langue:EN
Publié: BMC 2021
Sujets:
HIV
Cell-associated HIV-1 RNA
Cell-associated HIV-1 DNA
Genetic variants
Quantitative trait locus
Medicine
R
Accès en ligne:https://doaj.org/article/9d335b9fadb540eeb1f023c64679c30e
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https://doaj.org/article/9d335b9fadb540eeb1f023c64679c30e

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