A Targeted Computational Screen of the SWEETLEAD Database Reveals FDA-Approved Compounds with Anti-Dengue Viral Activity

ABSTRACT Affordable and effective antiviral therapies are needed worldwide, especially against agents such as dengue virus that are endemic in underserved regions. Many antiviral compounds have been studied in cultured cells but are unsuitable for clinical applications due to pharmacokinetic profile...

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Main Authors: Jasmine Moshiri, David A. Constant, Bowen Liu, Roberto Mateo, Steven Kearnes, Paul Novick, Ritika Prasad, Claude Nagamine, Vijay Pande, Karla Kirkegaard
Format: article
Language:EN
Published: American Society for Microbiology 2020
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Online Access:https://doaj.org/article/9d33b3a657f445fa99ed33577dd68fd2
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