Soluble epoxide hydrolase inhibition decreases reperfusion injury after focal cerebral ischemia
Abstract Epoxyeicosatrienoic acids (EETs) are produced by cytochrome P450 epoxygenases from arachidonic acid, and their rapid metabolism is mainly through soluble epoxide hydrolase (sEH). EETs exert vasodilatory, anti-inflammatory, anti-apoptotic, and pro-angiogenic effects. Administration of sEH in...
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| Auteurs principaux: | , , , , , |
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| Format: | article |
| Langue: | EN |
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Nature Portfolio
2018
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| Accès en ligne: | https://doaj.org/article/9d390b315d5e4a4193980594c7cc235f |
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