STAT3 determines IL-4 signalling outcomes in naïve T cells

Abstract IL-4 production is associated with low-avidity, poorly cytotoxic T cell induction that contributes to viral immune evasion and the failure of T cell-based vaccines. Yet, the precise mechanisms that regulate IL-4 signalling in T cells remain elusive. Mounting evidence indicates that cells ca...

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Autores principales: Lachlan P. Deimel, Zheyi Li, Sreeja Roy, Charani Ranasinghe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/9d3a69cae7d44875ab35f73cf32c12c7
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