STAT3 determines IL-4 signalling outcomes in naïve T cells
Abstract IL-4 production is associated with low-avidity, poorly cytotoxic T cell induction that contributes to viral immune evasion and the failure of T cell-based vaccines. Yet, the precise mechanisms that regulate IL-4 signalling in T cells remain elusive. Mounting evidence indicates that cells ca...
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Autores principales: | Lachlan P. Deimel, Zheyi Li, Sreeja Roy, Charani Ranasinghe |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/9d3a69cae7d44875ab35f73cf32c12c7 |
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