Prediction of deleterious non-synonymous SNPs based on protein interaction network and hybrid properties.

Non-synonymous SNPs (nsSNPs), also known as Single Amino acid Polymorphisms (SAPs) account for the majority of human inherited diseases. It is important to distinguish the deleterious SAPs from neutral ones. Most traditional computational methods to classify SAPs are based on sequential or structura...

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Autores principales: Tao Huang, Ping Wang, Zhi-Qiang Ye, Heng Xu, Zhisong He, Kai-Yan Feng, Lele Hu, Weiren Cui, Kai Wang, Xiao Dong, Lu Xie, Xiangyin Kong, Yu-Dong Cai, Yixue Li
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/9d419a84d9284c4ba304fe00b716ff45
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