Normal myeloid progenitor cell subset-associated gene signatures for acute myeloid leukaemia subtyping with prognostic impact.

Acute myeloid leukaemia (AML) is characterised by phenotypic heterogeneity, which we hypothesise is a consequence of deregulated differentiation with transcriptional reminiscence of the normal compartment or cell-of-origin. Here, we propose a classification system based on normal myeloid progenitor...

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Auteurs principaux: Anna A Schönherz, Julie Støve Bødker, Alexander Schmitz, Rasmus Froberg Brøndum, Lasse Hjort Jakobsen, Anne Stidsholt Roug, Marianne T Severinsen, Tarec C El-Galaly, Paw Jensen, Hans Erik Johnsen, Martin Bøgsted, Karen Dybkær
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2020
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Accès en ligne:https://doaj.org/article/9d6f994c235e49a98003993006237fd0
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