Quantitative modeling predicts mechanistic links between pre-treatment microbiome composition and metronidazole efficacy in bacterial vaginosis

Bacterial vaginosis (BV) is typically caused by a shift in the vaginal microbiota from a Lactobacillus-dominant community to one colonised by strains of Gardenerella vaginalis and treatment with the antibiotic metronidazole (MNZ) often results in failure and recurrence. Here, the authors use modelli...

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Autores principales: Christina Y. Lee, Ryan K. Cheu, Melissa M. Lemke, Andrew T. Gustin, Michael T. France, Benjamin Hampel, Andrea R. Thurman, Gustavo F. Doncel, Jacques Ravel, Nichole R. Klatt, Kelly B. Arnold
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/9d83bafea6184047b1ac4bc5543da3b9
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